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A drug sold to prevent seizures and migraines was more effective than a placebo in reducing alcoholics’ heavy-drinking days, a study says.

Unlike other drugs to treat alcoholism, topiramate, or Topamax, does not require people to stop drinking before starting treatment, the study’s authors write in today’s Journal of the American Medical Association.

In addition, treatment required a weekly 15-minute counseling session, done by nurses in the study.

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TITUSVILLE, N.J. — OrthoMcNeil Neurologics Inc. and Johnson & Johnson Pharmaceutical Research & Development LLC are alerting prescribers and other health care professionals to the possibility of dispensing errors involving Topamax, Razadyne ER and Razadyne.
“Dispensing confusion between two drug products with similar brand names…

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Pregnant women who take the epilepsy drug topiramate may increase their newborn’s risk of birth defects, especially if they combine the drug with other epilepsy medications, according to a small study in this week’s Neurology.

Scientists who evaluated 203 women who became pregnant while taking topiramate, generic for Topamax, reported that of 178 babies born, 16 had major birth defects, including cleft palate and other …

CHICAGO — A migraine pill seems to help alcoholics taper off their drinking without detox treatment, researchers report, offering a potential option for a hard-to-treat problem.
The drug, Topamax, works in a different way than three other medications already approved for treating alcoholism.
Experts said the drug is likely to appeal to heavy drinkers who would rather seek help from their own doctors, rather than enter a rehab clinic to dry out. The drug costs at least $350 a month…

The most effective way to prevent further confusion between Topamax and Toprol-XL–the brand names of topiramate and metoprolol succinate–would be to change one of their names, according to Michael R. Cohen, president of the Institute for Safe Medication Practices.
A complete name change would not be necessary, Mr. Cohen said in an interview; capital letters co…

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> Topamax has been granted pediatric exclusivity from the Food and Drug Administration. The Ortho-McNeil Ne…

The FDA has approved Topamax tablets and sprinkle capsules as an add-on treatment for adults and children who suffer from seizures associated with Lennox-Gastaut Syndrome, a severe, debilitating form of epilepsy. The condition accounts for up to 10% of all cases of pediatric epilepsy.

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WALTHAM, Mass. — NeurAxon Inc., a developer of next generation pain therapeutics targeting neuronal nitric oxide synthase (nNOS), announced today the appointment of Robert Medve, M.D., to the newly created position of Chief Medical and Regulatory Officer of the Company. Dr. Medve was most recently Vice President of Science, Research and Development of Lifetree Clinical Research, a clinical research organization focused on clini…

Photo Credit: Bill Lloyd, MDHave you felt it?Recently there has been a run of pessimism on our WebMD Vision & Eye Disorders message board. An unusually large percentage of visitors are suffering, worried, frustrated, or all of the above. A common thread running through these messages is exhaustion…everything has been tried and there appears to be little more for their doctors…