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Pregnant women who take the epilepsy drug topiramate may increase their newborn’s risk of birth defects, especially if they combine the drug with other epilepsy medications, according to a small study in this week’s Neurology.

Scientists who evaluated 203 women who became pregnant while taking topiramate, generic for Topamax, reported that of 178 babies born, 16 had major birth defects, including cleft palate and other …